tested. The measured variables were assessed statistically in relation to whether the prostate volume was smaller (22 men) or larger (30 men) than 50 mL.
RESULTSPatients with a large prostate (mean 104 mL) had a higher mean arterial pressure (105 vs 95 mmHg, P < 0.01), and serum glucose (5.3 vs 4.8 mmol/L, P < 0.01) and serum cortisol (423 vs 362 nmol/L, P = 0.06) concentrations than those with a small gland (mean 31 mL). The personality test showed that they were also less assertive than the others ( P < 0.03). The components of the heart rate variability indicated that men with a large prostate had increased sympathetic activity.
CONCLUSIONMen with LUTS caused by a very large prostate have more risk factors for cardiovascular disease than those with a smaller gland.
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