No abstract

The detection of specific base sequences in human, viral, or bacterial DNA holds great importance in diagnosis of several diseases. Detection of infectious and inherited diseases at molecular levels provides reliable and early diagnosis. 1 A epoxy conducting composite material prepared from epoxy graphite modified with graphene oxide was developed. These composite electrodes were also successfully use for the voltammetry detection of oxidation signal of guanine of oligonucleotide encoding a region of HIV-1 proviral DNA in clinical samples. The results obtained in this study showed that the composite electrode used to detected biomarkers of viral diseases such as HIV-1.