No abstract

We have isolated a full-size cDNA coding for cardiac troponin T tcTnT) from a human adult heart library. using a slow skeletal TnT probe. This cDNA detected a 1.2 kb mRNA in fetal and post-natal human heart, the amount of whrch mcreased during ontogenic development.Interestingly, a stmilar transcrrpt was coexpressed in fetal skeletal muscle, together with the 0.9 kb slow skeletal muscle mRNA. and its expression was down-regulated during further development.