N-(Benzothiazol-2-yl)-4-chlorobenzenesulphonamide (NBTCS) was synthesized by condensation reaction of 4-chlorobenzenesulphonyl chloride and 2-aminobenzothiazole in acetone under reflux. Neodymium(III) and thallium(III) complexes of the ligand were also synthesized. Both ligand and metal complexes were characterized using UV-Vis, IR, 1H- and 13C-NMR spectroscopies, elemental analysis and molar conductance measurement. IR studies revealed that the ligand is tridentate and coordinates to the metal ions through nitrogen and oxygen atoms of the sulphonamide group and nitrogen atom attached to benzothiazole ring. The neodymium(III) complex displays a coordination number of eight while thallium(III) complex displays a coordination number of six. The ligand and its complexes were screened in vitro for their antibacterial activities against Escherichia coli strains (E. coli 6 and E. coli 13), Proteus species, Staphylococcus aureus and Pseudomonas aeruginosa using the agar well diffusion technique. The synthesized compounds were found to be more active against the microorganisms screened relative to ciprofloxacin, gentamicin and co-trimoxazole.

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Copper(II) complexes of bis(4-hydroxypent-2-ylidene)diaminoethane (BHPDE) were prepared by extractive method. Job’s continuous variation and equilibrium constant methods, as well as spectral and elemental analyses were applied in the determination of the nature of extracted species. The results indicate the formation of mixed ionic complexes of the types Cu(H2L)X2, Cu(H2L)2X2and CuL (where H2L = BHPDE and X = NO3-, CIO4-, Cl-or ½SO42-). Cu(H2L)X2and Cu(H2L)2X2predominate at low pH extractions while CuL chelate predominates at high pH extraction. The complexes exist in two isomeric forms, the blue readily-water-soluble and the violet less water-soluble forms. Both complexes show maximum absorption at 540 nm and molar absorptivity values of about 2.0 x 102dm3mole-1cm-1.

_____________________________________________________________________________Their solubilities and melting points were also determined.