Candidiasis is an infection caused by overgrowth of Candida species in the oral cavity dominated by C. albicans. One way to inhibit the growth of the fungi is by utilizing medical plants that contain antifungal compounds. Cocoa leaves is a plants that has antifungal compounds such as caffeine, flavonoids and alkaloids. The aim of study was analyzing the effect of cocoa leaf extract on the growth of C. albicans and determining the optimal concentration of cocoa leaf extract in inhibiting the growth of C. albicans. The study used macerated cocoa leaf extract. The inhibitive testing method conducted by disc diffusion method. The concentrations of cocoa leaf extract were 25%, 50%, 75%, 100%, and nystatin was used as positive control and aquadest was negative control. All were possed on the disc and further incubated for 24 hours. The inhibition effect was measured by a caliper. Cocoa leaf extract can inhibit the growth of C. albicans, and the largest co-concentration in inhibiting C. albicans was 100%.

Pendahuluan: Merokok merupakan salah satu kebiasaan yang sering dilakukan oleh masyarakat, termasuk kelompok lanjut usia (lansia). Kebiasaan merokok dapat mempengaruhi sekresi saliva pada lansia yang secara fisiologis mengalami penurunan sekresi saliva dan penipisan epitel mukosa mulut karena proses penuaan. Perubahan sekresi saliva dan penipisan epitel mukosa mulut dapat meningkatkan resiko infeksi rongga mulut seperti kandidiasis oral. Tujuan penelitian ini adalah untuk menganalisis perbedaan sekresi saliva melalui pengukuran laju aliran saliva serta terjadinya kandidiasis oral pada pasien lansia perokok dan bukan perokok, di Rumah Sakit Gigi Mulut  Universitas Jember (RSGM UNEJ). Metode: Penelitian ini merupakan analitik observasional pada pasien lansia RSGM UNEJ di Bagian Penyakit Mulut meliputi status merokok, pengukuran laju aliran saliva unstimulated, dan insidensi kandidiasis oral berdasarkan hasil pemeriksaan mikrobiologi oral swab. Populasi dalam penelitian ini adalah seluruh pasien lansia RSGM UNEJ Bagian Penyakit Mulut periode September 2019-Januari 2020. Metode pengambilan sampel yang digunakan adalah  total sampling. Hasil: Hasil uji Mann-Whitney menunjukkan tidak ada perbedaan signifikan antara sekresi saliva unstimulated pasien lansia perokok dan bukan perokok. Terdapat perbedaan kejadian kandidiasis oral antara pasien lansia yang merokok dengan yang tidak merokok (nilai p=0,065; derajat kepercayaan=90%). Simpulan: Tidak terdapat perbedaan laju aliran saliva pada lansia perokok dan bukan perokok, namun terdapat perbedaan terjadinya kandidiasis oral antara lansia perokok dan bukan perokok.Kata kunci: Laju aliran saliva, merokok, kandidiasis oral, lansia. ABSTRACTIntroduction: Smoking is one of the habits often carried out by the community, including the elderly. Smoking habits can affect salivary secretion in the elderly, who physiologically experience decreased salivary secretion and thinning of the oral mucosal epithelium due to the ageing process. The salivary secretion change and thinning of the oral mucosal epithelium can increase the risk of oral infections such as oral candidiasis. The purpose of this study was to analyse the differences in salivary secretion by measuring the salivary flow rate and the occurrence of oral candidiasis in elderly smokers and nonsmokers at the University of Jember Dental Hospital. Methods: This study was an observational analytic study in elderly patients of the Department of Oral Diseases University of Jember Dental Hospital, including the smoking status, measurement of unstimulated salivary flow, and the incidence of oral candidiasis based on the results of the oral microbiological swab. This study’s population were all elderly patients at the Department of Oral Diseases University of Jember Dental Hospital for September 2019-January 2020. The sampling method used was total sampling. Results: The Mann-Whitney test results showed no significant difference between the unstimulated saliva secretion of elderly smokers and nonsmokers. There was a difference in the incidence of oral candidiasis between elderly smokers’ patients and nonsmokers (p-value = 0.065; confidence level = 90%). Conclusion: There is no difference in the salivary flow rate in elderly smokers and nonsmokers, however, there are differences in the occurrence of oral candidiasis between elderly smokers and nonsmokers.Keywords: Salivary flow rate, smoking, oral candidiasis, elderly.

Insufficient dietary intake in school-age children can result in a weakened immune system, leading to susceptibility to illness. Children will easily be exposed to infectious diseases such as angular cheilitis. Jember has a large population of farmers, categorized as a low-paid occupation. The type of food consumed will affect each person's nutritional status. This study aims to identify the relationship between nutritional status and food intake with the prevalence of angular cheilitis in children grades I–III SDN 7 Nogosari in the agro-industrial setting of Jember. Analytical observation with a cross-sectional design was employed with 58 students as samples, whose nutritional health was assessed using the BMI/U index, visual examination angular cheilitis, and 24-hour recall method of food intake. The SPSS test was undertaken to investigate how variations in macronutrient and micronutrient consumption affect angular cheilitis in each nutritional status. Micronutrient intake that affected angular cheilitis had exceeded the RDA. Furthermore, the SPSS test showed no difference in the consumption of macronutrients and micronutrients in each nutritional status, supporting the occurrence of angular cheilitis at a rate of 0%. In the agro-industrial setting of Kebun Renteng, Jember Regency, students at SD Negeri 7 Nogosari grades I - III had a good nutritional profile with zero percent of angular cheilitis prevalence. It was impossible to determine the association between dietary status and the prevalence of angular cheilitis.

Smoking habit is a health problem that is found globally. Indonesia has the largest number of active smokers, reaching 65 million people. Fisherman is one of the occupation in Indonesia which have the largest proportion of active smokers, almost 44,5% compared to other occupation. Smoking habit triggers pathological conditions in the oral cavity. Smoking cause an inflammation of the palatal mucosa named nicotine stomatitis. The purpose was to determine the prevalence of nicotine stomatitis in fisherman at Puger Kulon and to find out the correlation between age, type of cigarette, the intensity of smoking and the incident of nicotine stomatitis in fisherman. Data were collected by interview with 301 respondents. Purposive sampling was used in this study. The chi- square test was used to examine the correlation between age, type of cigarette and the intensity of smoking with the incident of nicotine stomatitis. The prevalence of nicotine stomatitis in fisherman at Puger Kulon Village is 5.3% and age, type of cigarette, and intensity of smoking did not have a significant correlation to the incident of nicotine stomatitis in fisherman at Puger Kulon Village Puger District Jember Regency.