Objective: To evaluate changes in bone density and architecture in postmenopausal women with breast cancer (BC) and use of aromatase inhibitor (AI). Subjects and methods: Thirty-four postmenopausal women with BC, without bone metastasis, renal function impairment and who were not receiving bone-active drugs were selected from a population of 523 outpatients treated for BC. According to the presence of hormonal receptors, HER2 and Ki67, seventeen had positive hormonal receptors and received anastrozole (AI group), and seventeen were triple-negative receptors (non-AI group), previously treated with chemotherapy. Areal bone mineral density (aBMD) and vertebral fracture assessment (VFA) analyses were performed by DXA; vBMD and bone microarchitecture were evaluated by HR-pQCT. Fracture risk was estimated using the FRAX tool. Results: No patient referred previous low-impact fracture, and VFA detected one moderate vertebral fracture in a non-AI patient. AI patients showed lower aBMD and BMD T-scores at the hip and 33% radius and a higher proportion of osteoporosis diagnosis on DXA (47%) vs non-AI (17.6%). AI group had significantly lower values for vBMD at the entire, cortical and trabecular bone compartments, cortical and trabecular thickness and BV/TV. They also had a higher risk for major fractures and for hip fractures estimated by FRAX. Several HR-pQCT parameters evaluated at distal radius and distal tibia were significantly associated with fracture risk. Conclusion: AI is associated with alterations in bone density and microarchitecture of both the cortical and trabecular compartments. These findings explain the overall increase in fracture risk in this specific population.

. Athos da Silveira Ramos, 149 -Bloco A, sala A-509, 21941-909 -Rio de Janeiro -RJ. Arnaldo Alcover Neto, Coordenação de Análise Mineral, Centro de Tecnologia Mineral, Av. Pedro Calmon, 900, 21941-908 -Rio de Janeiro -RJ.Este trabalho apresenta um estudo da composição química de pilhas usadas fabricadas no Brasil e em países asiáticos. O objetivo era comparar a qualidade desses produtos. As amostras foram desmontadas antes da caracterização química. As pilhas asiáticas apresentam mais elementos, incluindo teores elevados de ferro, mercúrio, cádmio e chumbo, e teores mais baixos de manganês e zinco quando comparadas às pilhas nacionais. Portanto, as pilhas de origem asiática representam um risco maior ao meio ambiente. Além disso, apresentaram o pior desempenho no funcionamento de diversos equipamentos eletroeletrônicos. Aspectos sócioeconômicos explicam a existência de um mercado para as pilhas asiáticas no Brasil.Palavras-Chave: Pilhas, Composição Química, Metais Pesados ABSTRACT This work presents a study on the chemical composition of spent batteries manufactured in Brazil and Asian countries. The goal was to compare the quality of these products. Samples were disassembled prior to chemical characterization. The Asian batteries presented much more elements, including higher amounts of iron, mercury, cadmium and lead, and lower amounts of manganese and zinc than Brazilian batteries. Therefore, they present a higher environmental hazard. Also, their performance in several electroelectronic devices was much poorer than the Brazilian samples. Socio-economical aspects explain the considerable market for Asian batteries in Brazil. INTRODUÇÃOUma pilha é um dispositivo eletroquímico que converte energia química contida em seus materiais ativos em energia elétrica por meio de uma reação de oxirredução, fornecendo uma fonte portátil de energia com amplo uso em vários produtos eletroeletrônicos [1]. A unidade eletroquímica básica, conhecida como "célula", consiste de um anodo (eletrodo negativo), um catodo (eletrodo positivo) e um eletrólito (solução