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Performing physical exercise during hemodialysis has been debated regarding safety and efficacy for improving life quality for patients with chronic kidney disease (CKD). Thus, we explored the influence of physical exercise during hemodialysis on both autonomic modulation of heart rate and quality of life for patients with CKF in a randomized clinical trial. We randomly allocated participants requiring hemodialysis to an experimental exercise group (EG) and a control no-exercise group (CG) and assessed their quality of life with the Kidney Disease Quality of Life Short Form—KDQOL-SF™ 1.3 and with Polar RS800CX to monitor their heart rate variability (HRV) before and three months after the end of the exercise intervention. EG participants reported a significant increase in their quality of life ( p = .05, physical function, physical aspects, pain, emotional well-being, emotional function; p = .03, energy and fatigue) and showed HRV improvement ( p = .05, RMSSD, SDNN, and SD2; p = .004, SD1) after three months of exercise. Thus, we recommend supervised physical exercise during hemodialysis for carefully selected patients.

The city of Wuhan, capital of China's Hubei province, was the scene of an outbreak of a new coronavirus called the SARS-CoV-2 by the World Health Organization (WHO). Gradually, several countries developed strategies to reduce community contamination, including social isolation and lockdown. The purpose of this study is carry out a systematic review of studies that assessed quality of life in social distance during pandemics. A high sensitivity search was carried out in the main scientific databases associated with quality of life (MEDLINE via PUBMED, Embase, Lilacs, Scielo, PsycoInfo, Pepsic, Scopus e Cochrane Library).  The full-text versions were analyzed for methodological quality by two researchers independently and disagreement between reviewers was resolved by discussion or arbitration by the other researcher. Only cross-sectional studies that assessed health-related quality of life during SARS-CoV, MERS-CoV and SARS-CoV-2 outbreaks were included. Editorial, letter to the editor, point of view, case presentation or brief communication were excluded. 1072 studies were identified, of which 1067 were excluded following the PRISMA protocol, with 5 articles remaining at the end. Patients affected by SARS, MERS and COVID-19 had reduced quality of life and social distancing make it worse.

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