Stereological determination of glomerular density can be used as an accurate and objective method for studies regarding renal damage from ischemia. Warm ischemia during laparoscopic partial nephrectomy in pigs determined a significant reduction of glomerular density in the ipsilateral remaining parenchyma.

There was no significant difference in prognosis (DFS and OS rates) between the genders, but significant differences in sociodemographic and clinical characteristics were detected between male and female breast cancer cases.

Considering the malignant neoplasms observed in the oral cavity, squamous cell carcinoma (SCC) is the most diagnosed histological type. In 2018, 354,864 new cases of oral cancer were estimated worldwide, with an average of 70% in male patients. In the same year, the number of deaths was 177,384, of which 119,693 occurred in males and 57,691 in females (Bray et al., 2018).According to the National Cancer Institute of Brazil (INCA), considering the oral cavity as the primary location, 11,180 cases in men and 4,010 in women were estimated for 2021 in Brazil. In 2018, there were 1,975 cases of deaths from SCC in the tongue region, 77% of which were in males. In the southeastern region of Brazil, except for non-melanoma skin tumors, cancer of the oral cavity is the fifth most common in men and the 13th in women (INCA, 2019).

Background Low socioeconomic status, increasing age, and poor lifestyle behaviors are associated with poor survival in patients with oral cavity squamous cell carcinoma (OCSCC). To determine the overall survival (OS) and the risk of OCSCC death by tumor subsite. Material and Methods A retrospective cohort study of OCSCC patients diagnosed from 2007 to 2009 and treated at a single cancer center in Rio de Janeiro, Brazil. Patient information was obtained from the Hospital Cancer Registry (HCR) database and complemented by individual search of physical and electronic medical records. Descriptive statistics of population characteristics were computed. OS was estimated using the Kaplan-Meier method. Univariate and multivariate Cox proportional hazards regression analyses were used to estimate the risk of death by tumor subsite. Results Seven hundred and three patients with OCSCC were identified. Most patients were men (77.4%) with low levels of education (67.5%), who drank (73.9%) and smoked (79.7%). The most prevalent tumor site was the tongue (45.4%), 73.4% of patients had advanced (clinical stage III or IV) OCSCC at diagnosis and 74.1% died during follow-up. For the entire cohort, the OS was 39.1% at two years and 27.9% at five years. The median survival time was 1.4 years (95%CI: 1.2‒1.5). Non-operative treatment (HR: 3.11; 95%CI: 2.26‒4.29; p <0.001), advanced stage (HR 2.14; 95%CI 1.68-2.74; p <0.001), and age >60 years at diagnosis (HR: 1.37; 95%CI: 1.15‒1.64; p <0.001) were independently associated with the risk of death. However, these factors varied by tumour subsite. Conclusions Analysis of specific subsites of the oral cavity revealed substantial differences in prognostic factors associated with poor survival in OCSCC. Key words: Squamous cell carcinoma, oral cavity cancer, survival, prognosis.