We describe here the synthesis, characterization, bioconjugation, and application of water-soluble thioglycolic acid TGA-capped CdTe/CdS quantum dots (TGA-QDs) for targeted cellular imaging. Anti-human epidermal growth factor receptor 2 (HER2) antibodies were conjugated to TGA-QDs to target HER2-overexpressing cancer cells. TGA-QDs and TGA-QDs/anti-HER2 bioconjugates were characterized by fluorescence and UV-Vis spectroscopy, X-ray diffraction (XRD), hydrodynamic sizing, electron microscopy, and gel electrophoresis. TGA-QDs and TGA-QDs/anti-HER2 were incubated with cells to examine cytotoxicity, targeting efficiency, and cellular localization. The cytotoxicity of particles was measured using an MTT assay and the no observable adverse effect concentration (NOAEC), 50% inhibitory concentration (IC50), and total lethal concentration (TLC) were calculated. To evaluate localization and targeting efficiency of TGA-QDs with or without antibodies, fluorescence microscopy and flow cytometry were performed. Our results indicate that antibody-conjugated TGA-QDs are well-suited for targeted cellular imaging studies.

a b s t r a c tAn ultraviolet photodetector with an active layer of solution processed polymer:quantum dot hybrid is introduced. Poly[9,9-di-(2-ethylhexyl)-fluorenyl-2,7-diyl] represents the polymer and Zn 0.71 Cd 0.29 S is the quantum dot used for the device. Photophysical studies showed that an electron transfer from the polymer to the ternary quantum dot is thermodynamically favored. Quenching experiments performed between the polymer and quantum dot indicates the formation of a non-fluorescent complex with an association constant of 4.6 × 10 4 M −1 . The device structure of ITO/PEDOT:PSS/ADS231BE: 50 wt% Zn 0.71 Cd 0.29 S/Al yielded a photoresponsivity value of 324 mA/W at −4 V under 1 mW/cm 2 illumination at 365 nm at room temperature and this value is further increased to 380 mA/W as a result of annealing at 75 • C.

Chitosan has a very wide application range in different parts of life such as in biomedical and antimicrobial areas. In recent years the self-healing property of chitosan becomes more of an issue. In the study chitosan was used to obtain a self-healing composite material. An epoxy dye was converted to a self-healing coating. Different types of samples were prepared by coating the glass substrates with a polymer matrix reinforced with various amounts of chitosan. The samples were characterized by fourier transform Infrared (FTIR) and scanning electron microscope-energy dispersive spectroscopy (SEM-EDS). In addition, self-healing test was applied as a primary objective of this research. In this respect, the samples were scratched with a very thin pin, and they were analyzed by SEM periodically. It was observed that chitosan-reinforced dyes showed self-healing property. Mechanism of the self-healing process was also scrutinized.