These results confirm the relatively low incidence of SCADRs in China. Antibiotics, anticonvulsants and TCM are the most common causative drugs.

Radiation fields emitted by O, B-type stars or young stellar populations (SPs) are generally considered as significant central ionizing sources (CISs) of classic H II regions. In our previous studies, we show that the inclusion of binary interactions in stellar population synthesis models can significantly increase the ultraviolet spectrum hardness and the number of ionizing photons of intermediate-age (IA, 7 < ∼ log(t/yr) < ∼ 8) SPs. In this work, we present photoionization models of H II regions ionized by radiation fields emitted by IA SPs, and show that radiation fields of IA SPs, including binary systems, are in theory possible candidates of significant CISs of classic H II regions.When radiation fields of IA SPs comprising binary systems are used as the CISs of classic H II regions, the theoretical strengths of a number of lines (such as [O III]λ4959 ′ , [S II]λ6716 ′ , etc.), weaker than observations, are raised; the border /selection-criterion lines, between star-forming galaxies and AGNs in the diagnostic diagrams (for example, [N II]λ6583/Hα∼[O III]λ5007/Hβ), move into the region occupied originally by AGNs; and He II λ1640 line, observed in Lyman break and high-redshift gravitationally lensed galaxies, also can be produced.

Ichthyosis hystrix (IH) is characterized by spiny hyperkeratotic scale, and includes Brocq type, Lambert type, Curth-Macklin type, Rheydt type and Bäfverstedt type. The first documented cases of familial IH were of Lambert type. However, the ultrastructural features of IH Lambert type have not been reported. Three patients in two generations of a family from north China were observed. The patients showed widespread verrucose lesions without blister formation. The face, palms and soles were unaffected. This presentation strongly resembled IH Lambert type. The lesions faded dramatically in summer, without treatment. Light microscopic examinations showed binuclear cells and shell formation in the granular and upper spinous layers in all specimens, with similar findings in winter, when lesions were prominent, and in summer, when lesions had subsided. Electron microscopic examination revealed binuclear keratinocytes and concentric, thin to thick, unbroken shells of tonofilaments surrounding the nuclei, and segregation of cytoplasmic components. This family is the first with familial IH strongly resembling Lambert type to be reported in China. Binuclear cells and tonofilaments shells surrounding the nucleus in upper keratinocytes were characteristic features, which were similar to those reported in IH Curth-Macklin type. The basic histopathological defects were not changed despite significant clinical improvement of the lesion.

Subdwarf B stars (sdBs) can significantly change the ultraviolet spectra of populations at age t ∼ 1 Gyr, and have been even included in the evolutionary population synthesis (EPS) models by Han et al. (Mon. Not. R. Astron. Soc. 380:1098, 2007). In this study we present the spectral energy distributions (SEDs) of binary stellar populations (BSPs) by combining the EPS models of Han et al. (Mon. Not. R. Astron.