Micro-dissection technology possesses revolutionary significance in the research field about Cancer Genomics, through which pure population of targeted cells can be procured from tissue sections for subsequent analysis. In this paper, a novel Micro-dissection technology using ultrasonic vibration was proposed and the piezo-powered micro-dissection tool with its control and drive system were also developed. The micro-dissection tool employs the multilayer piezoelectric actuator for generating the ultrasonic vibration with high frequency and low amplitude. To control the piezo-powered Micro-dissection tool, a driving power for piezoelectric actuator was designed using direct digital synthesizer and direct current amplifying principle, thus the micro-dissection tool could vibrate with the frequency scope from 0.5k to50K and the amplitude scope from 0 to 2μm. Finally, experiments about bio-microdissection on liver tissue slice were carried out with the tool and better micro-dissection result was obtained. The experiments show the feasibility of the micro-dissection method with ultrasonic vibration. The new micro-dissection method can be adopted in the bio-micro-manipulation field and it can also significantly promote the development of Cancer Genomics.

This work is focused on design and fabrication of a hybrid-type electrostatic silicon microgripper integrated vacuum tool. Vacuum tools are integrated in this novel microgripper in order to improve its pick and place capability. Surface and bulk micromachining technology is employed to fabricate the microgripper from single crystal silicon wafer (i.e., no silicon on insulator wafer is used). And the bonding technology is used to form the gas pipes for the vacuum tool. The linear motion of the microactuator is converted into a rotational gripping motion by a system of spring beams. At a driving voltage of 80V, a deflection of 25μm at the arm tip of the gripper is achieved.

Iron loss will be rapidly increased when the permanent magnet iron core synchronous motor runs at a high speed, which makes the motor produce so much heat that causes low efficiency of the motor and even burns out the motor. The iron-core-free permanent magnet synchronous motor remedies this defect and has a high efficiency at high speed. This article makes a comparative analysis on the iron-core-free permanent magnet synchronous motor torque density with different slot engagement classifications. The paper puts forward an optimized model of permanent magnet synchronous motor without the iron core. The technology of the permanent magnet synchronous motor without iron core is studied based on this model which provides a method to design and manufacture the iron-core-free permanent magnet synchronous motor.

Dielectrophoresis (DEP) based microdevices offer a great number of significant advantages for the manipulation of biological particles such as cells, bacteria, viruses and DNA over traditional methods. To enable successfully dielectrophoretic manipulation of biological particles, electric fields of higher intensity need to be generated in order to increase the DEP forces. However, the introduced electric field may cause the joule heating effect and thermal denaturation of biological particles. This paper presents a numerical solution of the DEP force and the resulting electrical electrothermal driven fluid flow on a DEP microdevice. Theoretical investigations were made about the impact of electrothermal flow on DEP based microdevice. The fluid field was solved by coupling electrical, thermal, and mechanical equations. It is shown that under some typical experimental conditions of DEP based manipulation of biological particles, it is necessary to consider the possible influence of the electrothermal flow.

The heat of the positioning platform is mainly caused by conduction of each functional unit, when it affected by the influence of internal and external heat source at work, the temperature of units would change, and the condition would make the platform component stiffness change, then lead to positioning platform dynamic characteristics change. In this paper, the finite method analysis platform dynamic connection stiffness with the regularity of temperature change, and by using the grey correlation method to optimize the platform stiffness influence of the four largest temperature sampling point, through the neural network modeling method to establish high precision positioning platform stiffness model, provide theory for the research on platform of dynamic characteristics of the model.