Red pitaya (Hylocereus polyrhizus Weber Britton & Rose) is rich in antioxidants, which might help regulate oxidative stress, exacerbated in Diabetes Mellitus (DM). This study aimed to determine the centesimal composition, physicochemical characteristics and in vivo antioxidant effect of red pitaya in diabetic swiss mice. Pulp, seeds and peel were isolated and used for physicochemical and centesimal composition analysis. DM was induced in female Swiss mice through intraperitoneal Alloxan Monohydrate injection. Groups with 6 animals were formed: Healthy (SAUD), Untreated A and B (DNT A and DNT B), Metformin (MET), and groups fed with 20 (PIT20), 40 (PIT40), 200 (PIT200) and 400 (PIT400) mg of pulp with seeds extract/kg of animals’ body weight, by gavage, for 28 days. Thiobarbituric acid reactive species (TBARS) hepatic content was quantified by Malondialdehyde (MDA), to evaluate lipid peroxidation. Pitaya’s composition was similar to that previously reported. Pulp and peel showed insignificant lipid contents, expressive presence of carbohydrates, and fibers in all samples, especially peel. Lowest MDA was observed in PIT400, PIT200, and PIT40, compared to DNT A and B, and MET. Results were dose-dependent, suggesting pitaya consumption was associated with lower lipid peroxidation. Further studies on its composition and applications as a functional food are required, especially for humans and in DM.
A Residência Multiprofissional é uma importante estratégia de Educação Permanente (EPS) no Sistema Único de Saúde (SUS), sendo a primeira oportunidade para muitos recém-graduados de exercer sua profissão e adquirir experiência. O objetivo do presente estudo foi conhecer o perfil de profissionais egressos de um programa de Residência Multiprofissional em Cardiopneumologia no Ceará e sua inserção no mercado de trabalho. No estudo, transversal e quantitativo, coletaram-se dados socioeconômicos, sociodemográficos e sobre histórico no mercado de trabalho, entre junho e outubro de 2022, via formulário eletrônico enviado aos egressos. A grande maioria estava empregada, atuando no SUS como terceirizados, vinculados como celetistas ou cooperados, em áreas de atuação diversas, destacando o potencial de contribuição na saúde, na educação e na gestão pública. Estudos com profissionais egressos de outros programas hospitalares são necessários para melhor elucidar as potencialidades, contribuições e lacunas do processo formativo à inserção dos profissionais no mercado de trabalho.
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