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Electrospun polymeric scaffolds are used for various tissue engineering applications. In this study, we applied a biomimetic coating method to provide electrospun scaffolds from a block copolymer-poly(ethylene oxide terephthalate)-poly(buthylene terephthalate), with a calcium phosphate layer to improve their bioactivity in bone tissue engineering. The in vitro studies with human mesenchymal stem cells demonstrated cell proliferation on both uncoated and coated samples. No significant effect of calcium phosphate coating was observed on the expression of alkaline phosphatase in vitro. Implantation of scaffold-goat mesenchymal stem cells constructs subcutaneously in nude mice resulted in bone formation in the calcium phosphate coated samples, in contrast to the uncoated ones, where no new bone formation was observed. The results of this study showed that the biomimetic method can successfully be used to coat electrospun scaffolds with a calcium phosphate layer, which improved the in vivo bioactivity of the polymer.

Cellulose as the most abundant natural biopolymer on earth has shown promising potential because of its excellent physical, mechanical, and biocompatible properties, which are very important for sustainable energy storage systems (ESSs). In this review, a comprehensive summary of the applications involving all kinds and forms of cellulose in the advanced Na-related ESSs, including sodium ion batteries (SIBs) and sodium ion capacitors (SICs), is presented. For cellulose, the impact of various structures and surface chemical properties on the electrochemical performance is focused on. In particular, the latest developments in cellulose-based binders and separators are highlighted. In addition, an in-depth understanding of the structure and performance of electrode materials and the storage mechanism of a hard carbon anode derived from cellulose for SIBs is provided. Further, the manufacturing of full-cellulose-based SICs assembled by all parts of devices including hard carbon anodes, active carbon cathodes, binders, and separator based on cellulose or cellulose derivatives is reviewed. Finally, the prospects of cellulose-based energy storage systems on several issues that need further exploration are presented.

Bacterial infection is one of the greatest threats to public health. In vivo real-time monitoring and effective treatment of infected sites through non-invasive techniques, remain ac hallenge.H erein, we designed aP t II metallacyclebased supramolecular photosensitizer through the host-guest interaction between apillar[5]arene-modified metallacycle and 1-butyl-4-[4-(diphenylamino)styryl]pyridinium. Leveraging the aggregation-induced emission supramolecular photosensitizer,w ei mproved fluorescence performance and antimicrobial photodynamic inactivation. In vivo studies revealed that it displayed precise fluorescence trackingo fS .a ureus-infected sites,a nd in situ performed image-guided efficient PDI of S. aureus without noticeable side effects.T hese results demonstrated that metallacycle combined with host-guest chemistry could provideaparadigm for the development of powerful photosensitizers for biomedicine.