Background: The in vitro directive of the European Union requires traceability to the international recommended reference procedures. The application of the reference procedures is necessary in order to evaluate the accuracy of gglutamyltransferase (GGT) assays of routine measurement systems in China. Methods: Five frozen patient-pooled serum samples were assigned values by the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) reference procedure in order to evaluate the traceability of the results of GGT catalytic activity from six homogeneous systems. One of the serum samples was used to calibrate seven non-homogeneous systems.Results: All of the homogeneous systems, except the Dade system (Dade Bering Inc, IL, USA), achieved traceability within the measurement range. The Roche and Hitachi systems were better than the other systems. After calibration, the variance of the non-homogeneous systems decreased dramatically from between 14.50% and 25.23% to between 1.25% and 3.09% and the bias decreased from between 211.4% and 24.1% to between 0.5% and 3.5%. Conclusion: Manufacturers in China should ensure that their calibration systems correspond to the IFCC reference procedures. Fresh frozen pooled patient serum assigned by reference laboratories can be used to calibrate nonhomogeneous systems in order to achieve traceability.
This paper studies the buckling analysis for a ring-stiffened cylindrical shell consisted of functionally graded material (FGM) subjected to hydrostatic pressure and thermal loads. Material properties of the ring-stiffened FGM cylindrical shell are assumed to be temperature-dependent, and vary smoothly through the thickness direction of the structure according to a volume exponent. Based on the Donnell assumptions, buckling loads of the ring-stiffened FGM cylindrical shell are presented by utilizing the Galerkin method. Numerical results reveal that thermal loads, volume exponent and geometric parameters have significant effects on the buckling behavior of the ring-stiffened cylindrical shell.
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