The current study examined the roles of gender, and gender-role orientation in young adolescents’ empathetic concern. In addition, this study aimed to explore the contribution of Theory of Mind in participants’ empathetic concern. Finally, this study examined whether gender and gender-role orientation were implicated in emerging adolescents’ Theory of Mind understanding. One-hundred-fifty 11- to 12-year-olds (79 self-identified females) completed questionnaires measuring their empathetic concern, Theory of Mind, and their perceived gender-role orientation. Results showed that gender-role orientation, specifically, femininity and masculinity predicted empathetic concern above and beyond gender. In addition, the effects of cognitive and affective Theory of Mind are explored and discussed in relation to empathetic concern. Finally, neither gender nor gender-role orientation was found to contribute to participants’ Theory of Mind understanding. These findings suggest that emerging adolescents’ perceived gender roles, as well as their ability to consider another’s beliefs, play a role in their expression of empathetic concern.