Graphene materials have unique structures and outstanding thermal, optical, mechanical and electronic properties. In the last decade, these materials have attracted substantial interest in the field of nanomaterials, with applications ranging from biosensors to biomedicine. Among these applications, great advances have been made in the field of antibacterial agents. Here, recent advancements in the use of graphene and its derivatives as antibacterial agents are reviewed. Graphene is used in three forms: the pristine form; mixed with other antibacterial agents, such as Ag and chitosan; or with a base material, such as poly (N-vinylcarbazole) (PVK) and poly (lactic acid) (PLA). The main mechanisms proposed to explain the antibacterial behaviors of graphene and its derivatives are the membrane stress hypothesis, the oxidative stress hypothesis, the entrapment hypothesis, the electron transfer hypothesis and the photothermal hypothesis. This review describes contributions to improving these promising materials for antibacterial applications.

Abstract. With the evolution of an API library, its documentation also evolves. The evolution of API documentation is common knowledge for programmers and library developers, but not in a quantitative form. Without such quantitative knowledge, programmers may neglect important revisions of API documentation, and library developers may not effectively improve API documentation based on its revision histories. There is a strong need to conduct a quantitative study on API documentation evolution. However, as API documentation is large in size and revisions can be complicated, it is quite challenging to conduct such a study. In this paper, we present an analysis methodology to analyze the evolution of API documentation. Based on the methodology, we conduct a quantitative study on API documentation evolution of five widely used real-world libraries. The results reveal various valuable findings, and these findings allow programmers and library developers to better understand API documentation evolution.

We demonstrated, for the first time, that the short antimicrobial peptide Tet213 could be conjugated onto the silicon surface by Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC). The modified surface exhibited excellent antimicrobial activity against S. aureus and E. coli, and low cytotoxicity to rat bone mesenchymal stem cells (rBMSCs).

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