Recent life-change data were gathered from 279 survivors of documented myocardial infarctions and from 226 cases of abrupt coronary death in Helsinki. In nearly half of the infarction cases, recent lifechange data were also collected through a separate interview of spouses. Spouses provided the life-change data for all coronarydeath victims. In all but one group of subjects, marked elevations in magnitude of life changes during the six months immediately prior to infarction or death were seen, compared to the same time interval one year earlier. This elevation was particularly apparent for sudden-death victims. Women showed recent increases similar to those of men.

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599but we relieve the tension. Now the cause not being removed, and the humours continuing to augment, the intra-ocular pressure is of course re-established, and all those symptoms, with excavation of the optic nerve, &c. &c., must be re-established as well. In short, whilst the principle upon which De Grafe's operation is based is not quite clear, yet the operation itself must in the mean time be considered as the best at our command, until more light is thrown upon the pathological anatomy of glaucoma, to enable us to meet it by a rational system of medical treatment. I am, Sir, vours obedientlv.