Background: Mucociliary clearance is one of the defense mechanism of Eustachian tube mucosa.Eustachian tube disfunction is an important predisposing factor in the pathogenesis of recurrent otitismedia. Purpose: To find out the change of mucociliary clearence in active benign chronic suppurativeotitis media after conservative therapy. Method:Prospective experimental study in active benign CSOMwith sacharine 5% test, for the evaluation of mucociliary clearance time on day 1 and day 7 conservativetherapy. Result: The mean difference of mucociliary clearance time in the Eustachian tube was 608.94± 626.35 seconds (p<0.05) on day 7 of conservative therapy. Conclusion: The conservative therapy inbenign CSOM has shortened mucociliary clearance time.Key words: mucociliary clearance, mucociliary clearance time, chronic suppurative otitis media. Abstrak : Latar belakang: Mucociliar clearance merupakan salah satu bagian dari pertahanan mukosa tubaEustachius. Gangguan tuba Eustachius dapat merupakan faktor predisposisi penyebab otitis media yangberulang. Tujuan:Mengetahui perubahan waktu transpor mukosilia tuba Eustachius penderita otitismedia supuratif kronik (OMSK) benigna aktif, setelah pengobatan konservatif. Metode:Penelitianeksperimental prospektif pada penderita OMSK benigna aktif. Sampel penelitian mendapatkan perlakuanberupa tes sakarin 5% untuk menilai waktu transpor mukosilia tuba Eustachius pada hari pertama danketujuh pengobatan konservatif. Hasil: Perbedaan rata-rata transpor mukosilia tuba Eustachius sebelumdan sesudah pengobatan adalah 608,94±626,35 detik (p<0,05). Kesimpulan:Pengobatan konservatifdapat memperpendek waktu transpor mukosilia tuba Eustachius pada penderita OMSK benigna aktifyang berbeda secara signifikan.Kata kunci: mucociliar clearance, waktu transpor mukosilia, otitis media supratifkronik.
Background: Infection of the tonsils is a fairly common problem in the population. The complaints among others are pain while swallowing, fever, otitis media, until obstructive sleep apnea. Until now tonsillectomy procedure is still a controversy. For those against it, tonsillectomy is considered decreasing the body’s defense mechanism. Purpose: The goal of the research is to analyze the secretory immunoglobulin A level on the chronic tonsillitis patients before and after tonsillectomy.Method: The research was conducted as a comparative analytic study among the chronic tonsillitis patients before and after tonsillectomy. Result: The result of this study reveals that the level of secretory Ig A in healthy subjects were 5358.2200 + 1071.23 ng/ml, in chronic tonsillitis patients before tonsillectomy were 7539.6563 + 2293.07 ng/ml, and after tonsillectomy were 5946.4375 + 2133.13 ng/ml. Conclusion: The level of s-IgA in chronic tonsillitis prior to tonsillectomy was high and 4 weeks post operation the level of s-IgA decreased, close to the level of normal subjects. Keywords: secretory immunoglobulin A, chronic tonsillitis, tonsillectomy Abstrak : Latar belakang: Infeksi pada tonsil merupakan masalah yang cukup sering dijumpai. Keluhan yang ditimbulkan berupa nyeri menelan, demam, otitis media, sampai obstructive sleep apnea. Sampai saat ini tonsilektomi masih menimbulkan kontroversi. Bagi yang kontra, tonsilektomi dianggap dapat menurunkan sistem pertahanan tubuh. Tujuan: Mengetahui kadar Imunoglobulin A sekretori (s-IgA) pada penderita tonsilitis kronik sebelum dan setelah tonsilektomi. Metode: Analitik komparatif yang dilakukan pada penderita tonsillitis kronik sebelum dan setelah tonsilektomi. Hasil:Kadar s-IgA individu sehat adalah 5358.2200 + 1071.23 ng/ml, s-IgA penderita tonsilitis kronik sebelum tonsilektomi adalah 7539.6563 + 2293.07 ng/ml, sedangkan s-IgA penderita tonsilitis kronik setelah tonsilektomi adalah 5946.4375 + 2133.13 ng/ml. Kesimpulan: s-IgA penderita tonsilitis kronik sebelum tonsilektomi kadarnya tinggi. Empat minggu setelah operasi, kadar s-IgA turun mendekati kadar s-IgA individu normal. Kata kunci: imunoglobulin A sekretori, tonsillitis kronik, tonsilektomi
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