Purpose/Objectives-To describe the Heiney-Adams Recruitment Framework (H-ARF); to delineate a recruitment plan for a randomized, behavioral trial (RBT) based on H-ARF; and to provide evaluation data on its implementation.Data Sources-All data for this investigation originated from a recruitment database created for an RBT designed to test the effectiveness of a therapeutic group convened via teleconference for African American women with breast cancer.Data Synthesis-Major H-ARF concepts include social marketing and relationship building. The majority of social marketing strategies yielded 100% participant recruitment. Greater absolute numbers were recruited via Health Insurance Portability and Accountability Act waivers. Using H-ARF yielded a high recruitment rate (66%).Conclusions-Application of H-ARF led to successful recruitment in an RBT. The findings highlight three areas that researchers should consider when devising recruitment plans: absolute numbers versus recruitment rate, cost, and efficiency with institutional review board-approved access to protected health information.Implications for Nursing-H-ARF may be applied to any clinical or population-based research setting because it provides direction for researchers to develop a recruitment plan based on the target audience and cultural attributes that may hinder or help recruitment.Recruitment, particularly minority accrual, is the Achilles heel of research (Mills et al., 2006; U.S. Department of Health and Human Services, 2000). Accrual to national cooperative clinical trials is 5%-10% (Peppercorn, Weeks, Cook, & Joffe, 2004), and accrual to cancer control and behavior studies ranges from 14%-41% (Carlson, Speca, Patel, & Goodey, 2004;Keyzer et al., 2005;Linden et al., 2007;Margiti et al., 1999;Motzer, Moseley, & Lewis, 1997;Ott, Twiss, Waltman, Gross, & Lindsey, 2006;Richardson, Post-White, Singletary, & Justice, 1998) with few exceptions (Gil et al., 2006). African American participation in studies usually is 5% or less (Bakitas et al., 2009;Blacklock, Rhodes, Blanchard, & Gaul, 2010;Dirksen & Epstein, 2008;Powell et al., 2008). Although multiple and costly efforts have been instituted to increase accrual, researchers still are challenged to meet sample size requirements for their studies. Multiple barriers, such as patient, clinician, system, and trial design, have been cited as contributing to an inability to reach recruitment goals (Advani et al., 2003;BeLue, This material is protected by U.S. copyright law. To purchase quantity reprints, reprints@ons.org. For permission to reproduce multiple copies, pubpermissions@ons.org. Taylor-Richardson, Lin, Rivera, & Grandison, 2006;Cudney, Craig, Nichols, & Weinert, 2004;Dancy, Wilbur, Talashek, Bonner, & Barnes-Boyd, 2004;Heiney et al., 2006;Lichtenberg, Brown, Jackson, & Washington, 2004;Linden et al., 2007;Sears et al., 2003). In addition, knowledge of the unethical research conducted during the U.S. Public Health Service Tuskegee Research Project syphilis study often is cited as a reason for n...