Stent placement for coarctation of aorta is an effective treatment option, though it remains a technically challenging procedure. Technical and aortic complications have decreased over the past 3 years due to, in part, improvement in balloon and stent design. Improvement in our ability to assess aortic wall compliance is essential prior to placement of ISs in older patients with coarctation of the aorta.
Abnormalities were observed at intermediate follow-up following IS placement for treatment of native and recurrent coarctation of the aorta. Not exceeding a balloon:coarctation ratio of 3.5 and avoidance of prestent angioplasty decreased the likelihood of encountering an abnormal follow-up imaging study in patients undergoing intravascular stent placement for the treatment of coarctation of the aorta. We recommend IAI for all patients undergoing IS placement for treatment of CoA.
The development of the brain, particularly the protracted maturation of the prefrontal cortex (PFC), supports the development of episodic memory. Yet how different regions of the PFC functionally mature to support age-related increases in memory performance remains unclear. We investigated the PFC contribution to subsequent memory (SM) of encoded visual scenes in children, adolescents, and young adults (n = 83). We identified distinct patterns of PFC activations supporting SM: regions in the lateral PFC showed positive SM effects, whereas regions in the superior and medial PFC showed negative SM effects. Both positive and negative SM effects increased with age. The magnitude of negative SM effects in the superior PFC partially mediated the age-related increase in memory. Functional connectivity between lateral PFC and regions in the medial temporal lobe (MTL) increased with age during successful memory formation. In contrast, functional connectivity between the superior PFC and regions in the MTL decreased with age, suggesting an age-related increase in the anti-correlation between these regions. These findings highlight the differential involvement of regions within the PFC supporting memory formation.
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