This review presents an updated scenario of findings and evolutions of encapsulation of bioactive compounds for food and agricultural applications. Many polymers have been reported as encapsulated agents, such as sodium alginate, gum Arabic, chitosan, cellulose and carboxymethylcellulose, pectin, Shellac, xanthan gum, zein, pullulan, maltodextrin, whey protein, galactomannan, modified starch, polycaprolactone, and sodium caseinate. The main encapsulation methods investigated in the study include both physical and chemical ones, such as freeze-drying, spray-drying, extrusion, coacervation, complexation, and supercritical anti-solvent drying. Consequently, in the food area, bioactive peptides, vitamins, essential oils, caffeine, plant extracts, fatty acids, flavonoids, carotenoids, and terpenes are the main compounds encapsulated. In the agricultural area, essential oils, lipids, phytotoxins, medicines, vaccines, hemoglobin, and microbial metabolites are the main compounds encapsulated. Most scientific investigations have one or more objectives, such as to improve the stability of formulated systems, increase the release time, retain and protect active properties, reduce lipid oxidation, maintain organoleptic properties, and present bioactivities even in extreme thermal, radiation, and pH conditions. Considering the increasing worldwide interest for biomolecules in modern and sustainable agriculture, encapsulation can be efficient for the formulation of biofungicides, biopesticides, bioherbicides, and biofertilizers. With this review, it is inferred that the current scenario indicates evolutions in the production methods by increasing the scales and the techno-economic feasibilities. The Technology Readiness Level (TRL) for most of the encapsulation methods is going beyond TRL 6, in which the knowledge gathered allows for having a functional prototype or a representative model of the encapsulation technologies presented in this review.
An economic evaluation was conducted of flavanone and sugar production from orange peel (OP) using a sequential hydrothermal process. The process was conducted at laboratory (2 × 5 L), pilot (3 × 10 L), and industrial (3 × 500 L) scales. The results demonstrate that the scale‐up process decreased the cost of manufacturing (COM) with a significant increase in flavanone and sugar production. The lowest COM was of US$ 25.72/kg flavanones and US$ 1.43/kg sugars, both on an industrial scale. The predominant costs at the industrial scale (>90%) were the cost of utilities and the cost of raw materials. A low capital payback time was obtained, which decreased as return on investment and gross margin increased. A strengths, weaknesses, opportunities, and threats matrix demonstrates the relevant business topics related to the scale‐up of OP processing. Thus, the current scale‐up project can be considered as a promising approach to the production of flavanones and sugar from OP on an industrial scale. © 2020 Society of Industrial Chemistry and John Wiley & Sons Ltd
____________________________________________________________________________________________________________ RESUMOO transporte de cargas que move a economia do Brasil é conduzido com soberania através do sistema rodoviário, sobrelevando o motorista de caminhão a uma profissão de enorme importância para os diversos segmentos econômicos, em especial, para o agronegócio. O objetivo do presente trabalho foi avaliar as condições ergonômicas e ambientais dos postos de trabalho de motoristas de caminhão que atuam em atividades vinculadas ao agronegócio. O estudo de caso foi realizado na Fronteira Oeste com motoristas profissionais que executam tarefas no meio rural e agroindustrial. Para análise postural, executou-se filmagens e a geração de 240 fotos sequenciais como referencial do ciclo de atividade. Através do Software Ergolândia 6.0 as imagens foram analisadas pelo método RULA, que resultou na necessidade de intervenção na postura dos motoristas. Por meio do Questionário Bipolar foi observado que a atividade exercida pelos motoristas apresenta um quadro doloroso. Em relação as análises de ruído ocupacional e temperatura, nenhum parâmetro apresentou conforto aos indivíduos conforme a normalização da NR 17. Os valores de iluminação mostraram-se bastante deficientes devida à falta de uma norma específica para o interior da cabine de caminhões.
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