Science and Technology Parks (STPs) are of great importance in the business context of the region in which they carry out their activity. They are one of the main mechanisms of public and private initiatives for the promotion of research, development and innovation and transfer of technology. The main purpose of this type of institution is not a purely economic but also sociocultural benefit, which makes them an adequate investment from the point of view of public institutions. They promote the creation of companies and agreements with universities and research centers, generate jobs and attract technology-based companies. Therefore, they require a detailed assessment to understand their operation and generate action plans and models that new parks or those that are still in the early stages of growth may follow. Thus, this study focuses on identifying the main Critical Success Factors (CSFs) for STPs from a literature review and evaluating the importance of the main variables that appear in the literature on the advancement of STPs to group them according to its operational characteristics.