COVID-19 is one of the most relevant pathologies in recent months, becoming one of the most deadly pandemics that the world has faced; Since the detection of the first cases in Wuhan (China) until today, the evolution of those infected has been a bit unpredictable, although without a doubt comorbidities such as Diabetes Mellitus (DM) and Arterial Hypertension (HTN) have been an essential link in fatality of clinical evolutions and the main cause of transfer to intensive care units. A bibliographic analysis was carried out, using the Scielo, Scopus, EBSCO and Google Academic databases, where information was obtained from twenty-two bibliographic references in order to determine the influence of arterial hypertension and diabetes as risk factors in the evolution of patients with covid 19. Patients diagnosed with COVID-19 who have hypertension and diabetes as a personal medical history are more likely to develop complications during the course of the disease and even die. The control and isolation of these patients is of special importance, taking into account the risk posed by presenting these pathologies. The research work carried out in Cuba maintains the control and knowledge of the health personnel of the state of vulnerable patients.