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We included in a controlled study 38 consecutive patients aged up to 75 with newly diagnosed cancer of the prostate suitable for hormonal treatment (stage C-D). Patients were randomized to receive either flutamide and orchidectomy or flutamide alone. After 4 years the survival rate for the orchidectomy plus flutamide group (53%) appears to be better than for the group with flutamide alone (40%).

Extraventricular Neurocytoma (EVN) is a rare primary tumor of Central Nervous System (CNS). To date, no cases have been reported in International Literature, about EVN associated to meningoencephalocele as manifestation of subacute increased intracranial pressure.We report the fi rst case of EVN that manifested with diplopia and ocular motor disorders due to intraorbital meningoencephalocele through a bone gap in the orbital roof.Diagnosis of EVN is challenging and its differential diagnosis with more aggressive lesions is mandatory. Complete surgical removal does not need any adiuvant therapies and permits to control tumor growth and symptoms related to intracranial pressure.