A synergistic palladium/copper catalysis for asymmetric allylic alkylation of vinylethylene carbonates with aldimine esters has been developed for synthesis of α-quaternary (Z)-trisubstituted allylic amino acids under mild conditions. This methodology...

The asymmetric synthesis of multisubstituted allylic amino acid derivatives was accomplished by the allylic alkylation of a chiral glycine-based nickel complex with vinylethylene carbonates. The high level enantioselectivities and diastereoselectivities...

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