The configuration and performance of a new global atmosphere and land model for climate research developed at the Geophysical Fluid Dynamics Laboratory (GFDL) are presented. The atmosphere model, known as AM2, includes a new gridpoint dynamical core, a prognostic cloud scheme, and a multispecies aerosol climatology, as well as components from previous models used at GFDL. The land model, known as LM2, includes soil sensible and latent heat storage, groundwater storage, and stomatal resistance. The performance of the coupled model AM2–LM2 is evaluated with a series of prescribed sea surface temperature (SST) simulations. Particular focus is given to the model's climatology and the characteristics of interannual variability related to E1 Niño– Southern Oscillation (ENSO). One AM2–LM2 integration was performed according to the prescriptions of the second Atmospheric Model Intercomparison Project (AMIP II) and data were submitted to the Program for Climate Model Diagnosis and Intercomparison (PCMDI). Particular strengths of AM2–LM2, as judged by comparison to other models participating in AMIP II, include its circulation and distributions of precipitation. Prominent problems of AM2– LM2 include a cold bias to surface and tropospheric temperatures, weak tropical cyclone activity, and weak tropical intraseasonal activity associated with the Madden–Julian oscillation. An ensemble of 10 AM2–LM2 integrations with observed SSTs for the second half of the twentieth century permits a statistically reliable assessment of the model's response to ENSO. In general, AM2–LM2 produces a realistic simulation of the anomalies in tropical precipitation and extratropical circulation that are associated with ENSO.

This study revealed that clients believe antihistamines can be a useful part of multimodal therapy for canine atopic dermatitis. The results also demonstrated that a significant number of canines benefited from dietary modification. In addition, allergen-specific immunotherapy was the only treatment to induce true clinical remission of atopic dermatitis.

Objective To assess whether there is an association between veterinary specialty and the quality of life of residents in AVMA-Recognized Veterinary Specialty Organizations™ using the WHOQOL-BREF instrument. Methods This cross-sectional study used an online survey and data collection service for administration of the survey to veterinary residents during April 2021 to June 2021. Veterinary residents were contacted through their respective AVMA-Recognized Veterinary Specialty Organization™ and through social media. Overall quality of life along with the domains of Physical Health, Psychological Health, Social Relationships, and Environment were measured using the WHOQOL-BREF instrument. Additionally, data on the demographics of participants were collected and investigated as potential confounders. Mean standardized scores (0 to 100) were compared among the specialties using the general linear model. Results 792 residents from 21 veterinary specialties were included in the analysis. The results showed that overall quality of life and all four domains varied significantly among specialties after adjusting for significant demographic variables (all Ps < 0.001). The mean standardized overall quality of life score was 54.3, ranging from 31.8 in Emergency and Critical Care to 56.3 in Laboratory Animal. The mean standardized quality of life scores were lowest for Psychological Health (50.3), followed by Social Relationships (55.0), Environment (61.4), and Physical Health (62.6). Residents in Emergency and Critical Care had the lowest adjusted average scores in all quality of life domains. Residents in Internal Medicine, Anesthesia and Analgesia, and Surgeons had lower quality of life scores across several domains when compared to other specialties. Clinical relevance This study provides insight into the mental health and general well-being of veterinary residents. The results can assist veterinary specialty organizations, universities, and mentors in developing appropriate supporting programs for residents. The results can also assist residents in recognizing and more efficiently caring for their individual mental health and well-being.

Microscopic changes in the hair follicles of affected cats were consistent with self-induced trauma or barbering behaviour. All changes were reversible and paralleled findings associated with well-established, topical flea control products.

To the best of the authors' knowledge, this is the first report of a condition resembling ochronosis in a domestic animal species that has been evaluated with histopathology and advanced imaging techniques. It provides an additional differential in cases of aberrant pigmentation in cats.