8.04 ± 0.86 and 7.51 ± 0.78 5.74 ± 0.57 and 6.04 ± 0.51 mmol/L) were significantly higher than that of the control group (4.89 ± 0.32 mmol/L) (p < 0.05). SOD levels of the 136.39±13.48 and 145.87 ± 17.39 U/mg.pro) were significantly higher than that of the control group (108.41 ± 11.63 U/mg.pro) (p < 0.05). GPx levels of the POPtreated groups (68.24 ± 4.68, 71.33 ± 5.29 and 72.64 ± 5.99 U/mg.pro)
The present study was designed to determine the effects of polysaccharides from purslane (PFP) supplementation on acute exercise induced oxidative stress in young male Sprague-Dawley rats.
Animals were divided randomly into four groups, that is control group (C), low-dose PFP supplemented group (LP), middle-dose PFP supplemented group (MP) and high-dose PFP supplemented group (HP).Each group contains eight animals. The mice in the control group were orally administered physiological saline of 50 ml/kg bodyweight per day for 30 days, while the PFP supplemented group received the same volume of PFP of 100, 200 and 400 mg/kg bodyweight. On the final day of the study, rats were exercised to exhaustion (22 m/min at 10% inclination on the treadmill) and then all the rats were sacrificed. Body weight, running time, blood lactate, malondialdehyde (MDA), superoxide dismutase (SOD), and glutathione peroxidase (GPX) of rats were measured. Results of the above study showed that PFP supplementation could elevate the exercise tolerance and inhibited the production of blood lactate during acute exercise. PFP supplementation lowers exercise induced oxidative stress by means of decreasing SOD, GPX activities and MDA level in skeletal muscle of young rats.
The objective of this study was to investigate the effects of crude polysaccharides from Purslane (PFP) supplementation on fatigue induced by forced swimming in mice. 96 mice were divided randomly into four groups: Control group (CG), low-dose PFP supplemented group (PFP-LG), middle-dose PFP supplemented group (PFP-MG) and high-dose PFP supplemented group (PFP-HG). Each group contains 24 animals. All were administered orally and daily for 4 weeks. Control group received isotonic saline solution (50 ml/kg bodyweight); and supplemented groups orally obtained 100, 200 and 400 mg/kg bodyweight of PFP in appropriate volumes of physiological saline. Changes of the body weights of the mice were observed during initial and terminal stages of the experiment along with the swimming capacity and corresponding biochemical parameters including blood lactic acid (BLA), serum urea nitrogen (SUN) and hepatic glycogen. The results of this study showed that PFP supplementation could extend the swimming time to exhaustion of the mice, as well as increase the hepatic glycogen contents, while decreasing the BLA and SUN contents. These indicated that PFP could alleviate fatigue induced by forced swimming in mice.
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