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The radionuclide Technetium 99m was used to detect occult infiltrations of Kaposi's sarcoma in the subcutaneous and muscular tissues as well as draining lymph nodes. This allowed for large field Co‐60 teletherapy to encompass both the clinically evident as well as occult regional deposits of tumor. Seven patients were studied with an initial histologic diagnosis of Kaposi's sarcoma. One patient who had a negative isotope study was later proven to have dermal metastasis from renal carcinoma. There were no false positive or false negative results.

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