In extracted bovine incisors, NaOCl gel penetrated less into dentinal tubules than NaOCl solution. The addition of surfactants did not increase the penetration depth. The use of PUI significantly increased NaOCl penetration into dentinal tubules.
Diabetes mellitus is a disease characterized by persistent hyperglycemia, which may lead to brain tissue damage due to oxidative stress and also contributes to neuronal death and changes in synaptic transmission. This study evaluated the effect of oxidative stress and the use of antioxidants supplementation on myosins expression levels in the brains of chronic diabetic rats induced by streptozotocin. Lipid peroxidation, antioxidant enzymes activities, and myosins-IIB and -Va expressions at transcriptional and translational levels were examined after 90 days induction. The chronic effect of the diabetes led to the upregulation of superoxide dismutase (SOD) and catalase (CAT) activities, and the downregulation of glutathione peroxidase (GPx), but there was no statistically significant increase in the malondialdehyde (MDA) levels. These alterations were accompanied by high myosin-IIB and low myosin-Va expressions. Although the antioxidant supplementation did not interfere on MDA levels, the oxidative stress caused by chronic hyperglycemia was reduced by increasing SOD and restoring CAT and GPx activities. Interestingly, after supplementation, diabetic rats recovered only myosin-Va protein levels, without interfering on myosins mRNA levels expressed in diabetic rat brains. Our results suggest that antioxidant supplementation reduces oxidative stress and also regulates the myosins protein expression, which should be beneficial to individuals with diabetes/chronic hyperglycemia.
O presente trabalho tem como objetivo realizar uma revisão bibliográfica acerca da origem e das propriedades do coco-da-baía, bem como uma análise minuciosa de duas atividades de produção, industrialização e consumo, de acordo com regiões e unidades federativas brasileiras. Tais análises têm como objetivo embasar o estudo sobre a produção de resíduos sólidos proveniente da comercialização do fruto, tanto para consumo de sua água como para o consumo de sua polpa (coco verde e coco seco, respectivamente). A revisão também incluiu a apresentação de uma solução para os citados resíduos: a pirólise. Fazendo uma análise crítica de diversos trabalhos que tratam deste assunto, entendeu-se que a pirólise dos resíduos é uma alternativa viável e ecologicamente correta, produzindo carvão, óleo e gás, produtos estes que podem ser utilizados como filtros ou combustíveis.
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