Radiographically occult and subtle fractures are a diagnostic challenge. They may be divided into (1) “high energy trauma fracture,” (2) “fatigue fracture” from cyclical and sustained mechanical stress, and (3) “insufficiency fracture” occurring in weakened bone (e.g., in osteoporosis and postradiotherapy). Independently of the cause, the initial radiographic examination can be negative either because the findings seem normal or are too subtle. Early detection of these fractures is crucial to explain the patient's symptoms and prevent further complications. Advanced imaging tools such as computed tomography, magnetic resonance imaging, and scintigraphy are highly valuable in this context. Our aim is to raise the awareness of radiologists and clinicians in these cases by presenting illustrative cases and a discussion of the relevant literature.

Mucormycosis is a rare life-threatening opportunistic infection caused by mycetes of the order Mucoraceae. It appears mainly in immunocompromised patients (hematologic malignancies, anemia, AIDS) and in cases of advanced diabetes. A delayed diagnosis may imply a worse prognosis, so an early detection is mandatory for an adequate treatment. Herein we present a rare case of multi-organ mucormycosis with pulmonary, renal, pancreatic and spleen involvement detected and assessed by 18 F-FDG PET/CT in a 24-years-old woman diagnosed of grey zone lymphoma (DLCBL/HL) who underwent an allogeneic stem cell transplantation. PET/CT with 18F-FDG was a key element in biopsy guide, final diagnosis and monitoring of response to therapy.

No abstract

No abstract

18 F-FDG PET-CT has become the main procedure for staging and monitoring treatment response in patients with lymphoma. It can differentiate between active disease and necrosis/fibrosis in after treatment residual masses, mainly in Hodgkin Lymphoma patients. Persistence of FDG uptake is very suggestive of resistance or recurrence. However, there can be also some false positives (FP). Non necrotizing Granulomatous Lymphadenitis (NNGL) is a sarcoidosis-like inflammatory reaction and it can be a FP cause in PET-CT monitorization of HL treatment response. Here we present a case of a patient with HL who was NNGL PET positive after stem cell transplantation.