Among patients with unstable angina or myocardial infarction without ST-segment elevation, prasugrel did not significantly reduce the frequency of the primary end point, as compared with clopidogrel, and similar risks of bleeding were observed. (Funded by Eli Lilly and Daiichi Sankyo; TRILOGY ACS ClinicalTrials.gov number, NCT00699998.).

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Although dilatation of the pulmonary artery (PA) is characteristic of pulmonic valve stenosis (PVS), the occurrence of a PA aneurysm in association with PVS is very rare. The authors describe a patient with severe, dome-shaped PVS who developed a 6.5 cm pulmonary trunk aneurysm. Long-term follow-up after surgical valvotomy demonstrated that the size of the aneurysm remained unchanged. Pertinent literature and implications on the natural history and management of these aneurysms are discussed.

After contemporary everolimus-eluting stent implantation, women and minorities experience a similar risk of 1-year MACE but a higher adjusted risk of recurrent ischemic events primarily because of nonstent-related MIs. Both clinical and angiographic factors and social determinants of health, including widowhood and insurance status, contribute to 1-year MACE among women and minorities.