BACKGROUND: Skin cancer is the most common neoplasm in Brazil, with increasing incidence in recent decades. Data on the incidence of squamous cell carcinoma are scarce in southern Santa Catarina. OBJECTIVE: To establish epidemiological data on squamous cell carcinoma in Tubarão, State of Santa Catarina. METHODS: A cross-sectional review was conducted on anatomical pathology reports, positive for squamous cell carcinoma of the skin, found in the local laboratories. A convenience sampling method was used for data collection, since all the pathology reports from the local laboratories between 1999 and 2009 were included. The collected variables included year of diagnosis, age, gender, city of origin, tumor site, histological type and subtype, lesion size, margin involvement and relapse. RESULTS: In total, 1,437 case reports were identified, most frequently in individuals between 70 and 79 years old. Patient morbidity was 69.5 per 100,000 population for the year 1999, and 136.7 per 100,000 population for the year 2009, which represents a 50 percent increase. The face was the most affected area and the most common histological subtype was the well-differentiated tumor. CONCLUSION: There were 1,437 reports of squamous cell carcinoma of the skin between 1999 and 2009, with a significant increase in patient morbidity. There was an association between male gender and location on the lip and ear, and between females and the occurrence of squamous cell carcinoma of the skin on the nose, and upper and lower limbs. There was a prevalence of margin involvement after resection in 18% of lesions.
Summary Introduction:?The oral breathing is a frequent symptom in childhood and has many alterations that compromise the child physical and cognitive development, negatively influencing from the oral breather, comparing her with the not oral breathers. Method:?Cross sectional study, prospective with a sample from 71 patients from 4 to 17 years, being 39 mouth breathers attended by otorhinolaryngologists and 32 patients not mouth breathers as the control group, evaluated as the quality of life through a questionnaire. Results:?The oral breathers presented more nasal problems, with the sleep and food, besides an greater average punctuation for snoring at night (p?0,0001), when compared to the control group. The prevalence of night snoring in the patients oral breathers was of 87,2%. The high punctuation in the scale of answers meant a worst quality of life. Conclusion:?The syndrome of the oral breather seems to be related to a negative impact in the quality of life, mainly for the nasal problems, with the sleep and eating. Future studies with the application of the same questionnaire have become needed for this to become as capable instrument of evaluation of the life quality from the patients in the matter.
Case report of three patients with inflammatory bowel disease who underwent treatment with biology therapy and developed respectively: non-Hodgkins lymphoma, colorectal adenocarcinoma, and cholangiocarcinoma after long-term follow-up. They demonstrated that data are currently inconclusive about the development of long-term anti-TNF neoplasias.
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