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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the resulting coronavirus disease 2019 (Covid-19) remains a global challenge. There are intense studies for finding effective prevention and treatment options worldwide. Therefore, infection prevention, prognostic parameters of infection complication and identification of successful treatment protocols need more investigations.Interpretation of laboratory parameters may support clinicians in prevention and treatment of the disease, will improve COVID 19 infection outcomes and may potentially decrease the death rate overall.Study results have shown that different laboratory parameters during the disease course are significantly changed. In critically ill patients, coagulation complications and coagulation/anticoagulation imbalance are characteristic also. According to the research results, vaccination offers the best option for COVID-19 control.In this review, some parameters, current therapeutic options, preventive methods of COVID 19 infection are discussed.

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Background Since 2012, Scientific-Research Skills Center (SRSC) of Tbilisi State Medical University (TSMU) conducts “Basic of scientific research skills” course for the students of TSMU. The activities and functions of the center are derived from the competence of basic medical education in the Bologna Process. The center is continuously developing Research-Skills teaching in both, theoretical and practical terms. Objectives We conducted a survey among medical students of TSMU to assess students' knowledge about research and attitudes towards the scientific research prior and after completing “Basics of Scientific Research skills”course; to evaluate the importance of the course and reveal students' possible motivation changes towards becoming future researchers. Results To accomplish this aim, we conducted survey in two phases, before and after completion of the module. 177 students of faculty of Medicine completed the self-administered pre- and post-test anonymously. The possible answers to the questions were graded by 1-5 points (5- maximum). According to the results, 58% of students graded the question about “importance of research” by maximum points in post-tests, as opposed to pre-test (42%). Before undertaking the course, 82% of surveyed students considered research as an integral part of medical science. while, this indicator increased till 92% after the course completion. The survey results also showed that the majority of students (60% pre-test; 74% post-test) are willing to participate in scientific research in future. Conclusions scientific research skills course has a positive impact on the development and advancing scientific research skills among medical students. The course helps students to understand the importance of scientific research in health care. The course needs further development and more emphasis on practical research skills such as fieldwork, students' involvement in ongoing research projects etc. Key messages Our study showed that Tbilisi State Medical University students consider scientific research as an extremely important course in their curricula. Based on our survey findings, SRSC will further improve the course and will strengthen scientific research approaches.

The aim: To review the biopsychosocial aspects of psychiatric comorbidity in patients with musculoskeletal conditions and recommend a relevant mental health action plan. Materials and methods: Keywords (orthopedics, psychiatry, mental health) were used to list down and analyze the literature in PubMed and Google Scholar. All types of articles, including original research, systematic reviews, and meta-analyses, along with gray literature dating back to 2000. We excluded studies reporting a significant conflict of interest and findings dispersed through popular media instead of peer-reviewed journals. Conclusions: The biopsychosocial aspects of the “bone – brain axis” need to be better addressed by means of a pragmatic approach involving all concerned parties and acknowledging the challenges and limitations along the way.