No abstract

A total of forty‐eight dogs were utilized to titrate and evaluate the activity of a new miticide, amitraz. The treatment was applied dermally and evaluated for efficacy against experimentally induced Demodex canis and Sarcoptes scabiei infestations. Five different concentrations (2000, 1000, 500, 250, 125 p.p.m.) of the active drug, N'—(2, 4‐dimethylphenyl)N—{[(2, 4‐dimethylphenyl) imino] methyl} ‐N‐methyl‐methanimidamide, were tested. The activity of amitraz was compared to a standard treatment, placebo treatment, and no treatment. A single dermal treatment with amitraz (all concentrations) indicated activity against both D. canis and S. scabiei. The lowest concentration of active drug (125 p.p.m.) was significantly less efficacious than the four higher concentrations (250, 500, 1000, 2000 p.p.m.). At the 250 p.p.m. (or higher) level the effectiveness of this new miticide was comparable to the standard treatment. The data indicate the 250 p.p.m. concentration is the optimal level and the recommended dilution for treatment of mange mites. Drug reactions related to amitraz were not observed.

No abstract

Endometrial cancer (EC) is second only to cervical carcinoma among the most commonly diagnosed malignant tumours of the female reproductive system. The available literature provides evidence for the involvement of 32 genes in the hereditary incidence of EC. The physiological markers of EC and coexisting diet-dependent maladies include antioxidative system disorders but also progressing inflammation; hence, the main forms of prophylaxis and pharmacotherapy ought to include a diet rich in substances aiding the organism’s response to this type of disorder, with a particular focus on ones suitable for lifelong consumption. Tea polyphenols satisfy those requirements due to their proven antioxidative, anti-inflammatory, anti-obesogenic, and antidiabetic properties. Practitioners ought to consider promoting tea consumption among individuals genetically predisposed for EC, particularly given its low cost, accessibility, confirmed health benefits, and above all, suitability for long-term consumption regardless of the patient’s age. The aim of this paper is to analyse the potential usability of tea as an element of prophylaxis and pharmacotherapy support in EC patients. The analysis is based on information available from worldwide literature published in the last 15 years.

FI may be used as an additional marker for OAB diagnosis. Neurourol. Urodynam. 36:198-202, 2017. © 2015 Wiley Periodicals, Inc.