Plants extracts are the one of the most important sources that have been used in both ancient and recent to many facture variants, types of medical drugs  and that was the aim of the current study to find safe, effective and available natural alternatives by measuring the therapeutic effect of the alcoholic extract of tannins before and after the acid hydrolysis of the extract, in laboratory mice experimentally infected with C. parvum  and using three therapeutic concentrations (2, 1.3, 1) mg / ml, and the alcoholic extract before the acid hydrolysis  proved  its therapeutic efficacy with a noticeable decrease in the number of Oocyst  excreted with the feces, as the Oocyst were no longer excreted from the ninth day of the treatment. Parasite Oocyst on the fifth day of treatment were treated by oral administration of the extract in infected mice, in the other hand the current study recorded that Cryptosporidiais as a common disease in the study area, with infection rate of 26%.

The current study was conducted during the period between from the beginning of October 2021 until the end of March 2022. The aim of the study was to measure the therapeutic efficacy of alcoholic and aqueous extracts from the local tannins Cupressus sempervirens for the treatment of experimental infected laboratory mice with Cryptosporidiosis. Through a significant decrease in the number of Oocyst of the parasite that causes infection Cryptosporidium parvum after oral administration of the aqueous and alcoholic extracts with three concentrations (2, 1.3, 1) mg/ml compared to MTZ drug, as the alcoholic extract proved its efficacy by stopping the shedding of parasite Oocyst at the ninth day of treatment with its total absence on the eleventh day of treatment, while the shedding of parasite Oocysts in the group treated with aqueous extract stopped on the eleventh day and completely absent on the thirteenth day of infection.