Gallbladder inflammation is most often determined by the presence of gallstones. Acalculous cholecystitisusually occurs in patients with multiple comorbidities or with an immunosuppressed status, and therefore itsevolution is faster and more severe compared to acute calculous cholecystitis. The presence of a fish bone intothe peritoneal cavity, through a gastrointestinal fistula is not very rare, but acute cholecystitis caused by a fishbone is unexpected. Here, we present the case of a 75-year old woman who had eaten fish two months beforeand presented at the Emergency Room with perforated acalculous cholecystitis and a right subphrenic abscess.The laparoscopic approach permitted the evacuation of the subphrenic abscess, bipolar cholecystectomy andremoval of a fish bone from nearby the cystic duct. Postoperative evolution was uneventful, with hospitaldischarge after five days. The patient was in good clinical condition at two months follow-up.

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Rosai-Dorfman disease (RDD) is a rare idiopathic benign disease, self-limited non-Langerhans cell histiocytosis, most frequently presented as a massive bilateral and painless lymphadenopathy, associated with fever and weight loss. Extranodal manifestations of RDD represents a true diagnosis challenge for clinicians and surgical pathologists. A 64-year-old female, known with arterial hypertension and type 2 diabetes, presented to our Surgery Clinic for a left arm painless cutaneous tumour, having its onset one year before, and rapidly enlarged in the last two months. Physical examination revealed a firm and elastic cutaneous nodular lesion of 4 x 2 cm in size, prominent to the skin, with central ulceration area of 10 x 5 mm, located on the posterior side of the left arm. Surgery was performed, with lymphoma as a differential diagnosis at intraoperative extemporaneous examination. The RDD disease diagnosis was considered at histopathological analysis and confirmed by immunohistochemistry. Herein, we describe a rare case of purely cutaneous RDD presenting as unique cutaneous ulcerative nodular lesion, surgical treated only, and without local relapse after one-year follow-up.