Introduction. Ovarian dysgerminoma is a rare malignant ovarian germ cell tumor with its peak incidence in young women. Abdominal pain, abdominal distention, and the presence of a palpable mass are common symptoms at presentation. Depending on the FIGO stage at presentation the prognosis of dysgerminomas after surgical treatment, adjuvant chemotherapy, and radiotherapy is promising. Case Presentation. A 7-year-old girl was presented at our clinic with abdominal pain in all abdominal quadrants. Later the pain localized in the region of her right ovary. CT scan revealed a massive formation which was connected to her right ovary. Conclusion. Although malignant ovarian germ cell tumours are rare in children, physicians must always consider the possibility of MOGT-occurrences. The clinical symptoms might not be specific: abdominal pain, abdominal distention, nausea, and vomiting. In order to make a correct diagnosis the patients should undergo a complete clinical examination including radiological scans. Initial management is frequently surgery, followed by adjuvant chemotherapy and radiotherapy. Although disgerminoma is malignant tumor, the prognosis is promising.

Background: Breast cancer is the most common cancer affecting women all over the world. It is estimated to account for around 25% of all malignancies in women, and its incidence shows a continuously increasing trend in many countries 52,7 % `ensk, ki `ivijo zunaj mest (p<0,01). Poznale so naslednje presejalne metode: klini~no preiskavo dojk (24,8 %), samopregledovanje dojk (12,6 %), mamografijo in ultrazvo~no preiskavo (5,0 %)

Small cell carcinoma (SmCC) is a poorly diff erentiated neuroendocrine carcinoma that has been reported in several sites throughout the head and neck region, including salivary glands where it is a rare primary tumor accounting for less than 1% of all salivary gland tumors. We report a case of a 55-yearold man with problems consisting of neck pain and diffi cult swallowing induced by a retromolar mass. Physical examination revealed an exophytic infi ltrative process in the right retromolar trigonum, measuring 2 centimeters in diameter. On cut surface the tumor was white and grayish. Microscopically, it was composed of sheets, ribbons and nests of mitotically active tumor cells set within a variably fi brous stroma. Th ere was a positive immunohistochemical reaction for broad spectrum keratin, EMA, synaptophysin and chromogranin. Th e combination of fi ndings was in favor of small cell neuroendocrine carcinoma with the probable origin from a small salivary gland. In the 2005 WHO classifi cation of head and neck tumors, SmCC of salivary glands is defi ned as a rare malignant epithelial tumor. Diff erential diagnosis includes metastatic pulmonary SmCC and cutaneous neuroendocrine carcinoma (Merkel cell carcinoma). Although salivary gland SmCC does not metastasize as frequently as pulmonary SmCC, locoregional metastases are present at diagnosis in as many as 50% of cases. SmCC arising in major or minor salivary glands has a better prognosis than pulmonary SmCC, but in our case the patient survived for just one month after the diagnosis. Th e autopsy confi rmed oropharynx as the primary location of the tumor. Besides multiple liver metastases, there were no signs of tumor anywhere else in the body. Clinically signifi cant metastases to thyroid gland are very rare. Th e incidence of thyroid involvement by metastatic disease ranges from an average of 3.1% in surgical series to 5.3% in autopsy series. Metastases to pre-existing thyroid neoplasms are distinctly uncommon. Malignant melanoma is one of the tumors that may metastasize to thyroid gland. We describe a case of a woman with thyroid metastases from a nodular melanoma discovered by fi ne-needle aspiration biopsy of thyroid nodule. Six months before, a 67-year-old woman was diagnosed with malignant nodular melanoma on the right upper arm. Axillary lymph nodes were positive. Follow-up examination revealed nodular enlargement of the right thyroid lobe. Fine-needle aspiration (FNA) showed the presence of epitheloid cells with nuclear atypia and cytoplasmic pigmentation. Morphological features suggested thyroid metastasis from malignant melanoma and thyroidectomy was performed. Pathologic examination revealed a completely encapsulated nodule measuring up to 1 cm in diameter, showing histopathologic features of follicular adenoma with no evidence of capsular or vascular invasion. Th e adenoma was infi ltrated by a nodule of immunohistochemically HMB45 positive malignant cells containing dark pigment. Th e incidental metastatic nodule was found in the opposite thyroid lo...