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For the busy NP, EBP has emerged as an important strategy to maintain valid, accurate, and relevant clinical knowledge. It is expected that this part of the series will enable NPs to identify appropriate databases to answer clinical inquires while refining their search strategy skills, which takes both time and practice.

The principles of EBP have become the cornerstone strategy for NPs to translate research findings into clinical practice. Practicing in an ever-changing healthcare environment, NPs have a responsibility to provide their clients with the best available evidence, while incorporating that evidence into the provider-client decision-making process.

Purpose: Evidence‐based practice (EBP) involves integrating research evidence with clinical expertise to answer clinical practice inquiries. The purpose of part 3 of this EBP series is to provide an introductory overview of the critical appraisal process, relevant clinical measurements, and critical thinking skills that can enhance nurse practitioners’ (NPs') confidence in the clinical decision‐making process. Data sources: Scientific literature review, gray literature, PubMed and other online literature databases and resources, and online EBP websites. Conclusions: Critical appraisal skills can assist NPs in interpreting available research, determining its validity reliability, and applicability to their clinical practice. Similarities in the critical appraisal process center around determining a study's reliability, validity, and applicability to the client(s) in question, while the differences exist in the clinical measurements used within specific research designs. Implications for practice: Because medicine is an evolving field, access to knowledge sources that address diagnostic, therapeutic, and prognostic questions is essential for the NP in order to maintain best practice skills. Making EBP user friendly for the practicing NP is paramount for utilization of best evidence.

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