Public reporting burden for the collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden, to Washington Headquarters Services, Directorate for Information Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to a penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number. REPORT DATE SEP 20052 PrefaceThis report provides an overview and analysis of 10 insider events that occurred prior to 2003 in infrastructure industries. It concludes with a set of observations that have clear implications for policies and management practices in government and industry. The 10 full case studies, authored by Eric D. Shaw, Ph.D., Consulting & Clinical Psychology, Ltd., are contained in another report that was issued as For Official Use Only in order to respect the confidentiality of private sector companies that were victimized by the offenders. These cases represent attacks against information systems that are essential for the functioning of national critical infrastructure industries.The threat to organizations in this category is obviously a Department of Defense (DoD) concern; however, insider attacks, not unlike those described here, have also occurred in military departments and Defense agencies. PERSEREC has been tracking events on the government side over the past 3 years and has a growing database of information on trust betrayal involving information systems. A subsequent summary of findings that pertain specifically to the Defense community will be issued at a later date. In the interim, case study work of the type and quality seen here is proving to be invaluable to our understanding of this behavior and of mitigating factors that we would recommend to minimize Defense systems vulnerabilities.The significance of the analysis of these events extends beyond a concern with the vulnerability of critical information technology (IT) systems. This is an attempt to understand one manifestation of the much larger insider threat to the DoD and the United States. Other dimensions of this threat include insider espionage-concerning which PERSERC has had a long-term research interest-and the insider threat associated with international terrorism that is only now emerging. These threats all stem from human problems and vulnerabilities that might be addressed in time to prevent damage or loss by an effective personnel security system working in harmony with employee assistance programs. For this reason, we are particularly interested in implications that focus on preemployment screening, m...

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The public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing the burden, to Department of Defense, Washington Headquarters Services, Directorate for Information Operations and Reports (0704-0188), 1215 Jefferson Davis Highway, Suite 1204, Arlington, VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to any penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number.

The Regenerative Medicine Manufacturing Society (RMMS) is the first and only professional society dedicated toward advancing manufacturing solutions for the field of regenerative medicine. RMMS's vision is to provide greater patient access to regenerative medicine therapies through innovative manufacturing solutions. Our mission is to identify unmet needs and gaps in regenerative medicine manufacturing and catalyze the generation of new ideas and solutions by working with private and public stakeholders. We aim to accomplish our mission through outreach and education programs and securing grants for public-private collaborations in regenerative medicine manufacturing. This perspective will cover four impact areas that the society's leadership team has identified as critical: (a) cell manufacturing and scale-up/out, respectively, for allogeneic and autologous cell therapies, (b) standards for regenerative medicine, (c) 3D bioprinting, and (d) artificial intelligence-enabled automation. In addition to covering these areas and ways in which the society intends to advance the field in a collaborative nature, we will also discuss education and training. Education and training is an area that is critical for communicating the current challenges, developing solutions to accelerate the commercialization of the latest technological advances, and growing the workforce in the rapidly expanding sector of regenerative medicine. K E Y W O R D S stem cells, technology, tissue engineering, tissue regenerationThis is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

The public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing the burden, to Department of Defense, Washington Headquarters Services, Directorate for Information Operations and Reports (0704-0188), 1215 Jefferson Davis Highway, Suite 1204, Arlington, VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to any penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1.REPORT PERSEREC examined the relationship between DoD security policy and federally mandated employee assistance programs (EAPs) for civilians and counseling/referral services for military personnel to identify any barriers for cleared DoD employees to using these programs. The study, based largely on interviews, but also on focus-group information and on a review of policy documents and other literature, found that policy is in place to help cleared individuals with personal problems get access to the counseling and treatment they need. However, research showed that cleared employees, civilian or military, often remain suspicious that their attendance at such programs will result in clearance revocation. Thus, some consult counseling programs outside the federal system, eschewing the very programs that the government has set up to help them. Report 1, designed for the policymaker, makes various recommendations for augmenting policy guidance, and for enhancing security education programs to underscore the fact that people can get help without putting their security status in danger. Report 2 documents the research and presents findings and conclusions; it also contains a series of appendices that provides background information for the interested reader on such topics as the EAP movement, military counseling/referral programs, and DoD personnel security policies and programs. PrefaceIn the wake of an alarming number of espionage cases involving cleared U.S. employees in the early-to-mid 1980s, the DoD Security Review Commission under the chairmanship of General Richard G. Stilwell, USA (Ret.) recommended that a personnel security research center be set up. In 1986 PERSEREC was established. The center was charged with producing data-based information for policymakers to facilitate making informed decisions on personnel security policy, with the ultimate aim of reducing the likelihood of people committing espionage.People are drawn to espionage for a variety of complex and interconnected reasons, many of which are caused by unresolved personal problems. Professional help-from programs and services provided by t...