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followed two weeks of active or placebo treatment at home, followed by post-treatment measurements. Then participants had two weeks with no intervention or placebo to wash-off any potential effects, followed by the repetition of the procedure with the other active or placebo device, again followed by two weeks of washout. The Wilcoxon signed-rank test was used to compare the change in pre to post-treatment measurement within subjects and between the active treatment and placebo. Values are mean (SD) in N. RESULTS: Under active treatment, strength significantly improved compared to the baseline (Pre,162.64 (37.51); Post,185.56 (33.95), p=0.01) and compared to the placebo (Active,22.64 (24.01); Placebo,-4.12 (32.24), p=0.02). No significant difference in strength was reported with placebo (p=0.68). Endurance time did not change significantly with either active treatment (p=0.52) nor placebo (p=0.85). CONCLUSIONS: Two-week administration of PBMT may improve muscle strength in persons with mild-moderate MS.