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In this post-marketing surveillance study, CSE-1034 was found to be an effective and safe option against Pip tazo and meropenem in management of patients with multi-drug resistant (MDR) bacterial infections under routine ward settings.

Overall assessment of clinical cure rate, microbiological eradication rate and safety assessment in this study has shown that CSE-1034 is an effective and safe option for the treatment of CAP patients of PORT risk III-IV. Moreover, the superiority of CSE-1034 over Ceftriaxone is also proven.

Objective: Metallic nanoparticles are usually synthesized by chemical methods which require toxic chemicals. The objective of present study was to prepare silver nanoparticles of leaves extract and evaluated for Ficus palmata antimicrobial and antioxidant activities. In this current research article we report the eco-Materials and methods: friendly green synthesis of silver nanoparticles from leaf extract of without using any external reducing Ficus palmata or capping agent. The synthesized nanoparticles were characterized by UV-Vis Spectroscopy, X-ray diffraction (XRD), Scanning Electron Microscopy and Transmission Electron Microscopy (TEM) techniques. UV-Vis Results: Spectroscopy studies showed the absorbance peak at 452 nm. The XRD patterns indicated the formation of crystalline silver nanoparticles having face-centered cubic geometry. The spherical nature and size of synthesized nanoparticles was further confirmed by TEM. The synthesized nanoparticles showed considerable antibacterial and Conclusion: antioxidant activities.

The plant may be considered a bio-synthetic laboratory, not only for the bio-chemicals such as carbohydrates, protein, and lipid that are utilized as food by man, but also for a multitude of compounds like glycosides, alkaloids, tannins etc, that exerts physiological effects. The compound those are responsible for therapeutic effects are usually the secondary metabolite. Bombex ceiba plant extracts have been evaluated for its antidiabetic properties by in-vitro inhabitation of alpha amylase and alpha glucosidase enzymes. The results so far obtained are encouraging by showing inhibition of these enzymes to a large extent. The water and ethanolic extracts of all the plant parts (thalamus and flower) show the highest inhibition as compared to DCM extracts.The corresponding IC50 values are as thalamus DCM extract 36.22, ethanolic extract 35.32, and water extract 31.31and the flower DCM extract 38.13, ethanolic extract 35.23, and water extract 33.00. The water, ethanolic and DCM extract of thalamus shows the concentration of sodium as 340, 310, 120 (ppm), potassium as 151, 180, 98 (ppm), lithium 31, 25, 11(ppm) and that of calcium 110, 80, 89 (ppm). The water, ethanolic and DCM extract of flower shows the concentration of sodium as 300, 295, 95 (ppm), potassium as 149, 175, 81 (ppm), lithium 28, 20, 05 (ppm) and that of calcium 95, 75, 64 (ppm).