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Prioritizing incorporation of patient preferences within guidelines holds good value and should be prioritized when developing new guidelines.

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Kanneganti et al. merged United Network for OrganSharing (UNOS) and Pediatric Health Information System (PHIS) data to perform the first assessment of center-level variation in acute rejection and biliary tract complications in the first year following pediatric liver transplantation. (1) By combining these data sources, these authors have (1) created a novel, robust data set for the longitudinal study of pediatric liver transplantation recipients and (2) identified potentially new opportunities for quality improvement in postpediatric liver transplantation morbidity. In their analysis, Kanneganti et al. found significant center-level variation in acute rejection and, to a lesser degree, in biliary complications in the year following pediatric liver transplantation. These data would suggest that centerspecific patient management after transplant is a critical driver of pediatric liver transplantation success. At first glance, these findings are expected and in and of themselves unlikely to foment great change. Although identification of high-performing centers in these arenas is a crucial first step to quality improvement efforts, the true innovation here is the novel data set created that can provide large, multicenter, and potentially longitudinal data on pediatric liver transplantation