Objective: To investigate the antiulcerogenic activity of methanolic extract of Brassica var. capitata rubra in albino rats.
Methods:To evaluate the antiulcer activity by pyloric ligation models experimentally induced gastric ulcer by ranitidine (10 mg/kg) subcutaneously. The parameters taken to assess antiulcer activity were free acidity, total acidity, volume of gastric juice, PH, ulcer score, and ulcer index.
Results:The methanolic extract of Brassica oleracea var. capitata rubra in the dose of 0.50 mg/kg produced significant antiulcer activity. The control animals had ulcers and hemorrhagic streaks, whereas in animals administered with extracts of B. oleracea there was a significant reduction in ulcer index (p˂0.05).
Conclusion:This study concluded that methanol extract of B. oleracea var. capitata has healing property of gastric ulcers in albino rats.
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