Commercial phantoms designed for radiologists to practise the skills needed to biopsy lesions under ultrasound guidance can be prohibitively costly, and do not have an indefinite shelf-life. A gelatin-based in-house model has been developed to recreate the conditions found in human tissues, using materials which are cheap and in everyday use. This phantom remains useful for several weeks, although tears produced by the biopsy needle take progressively longer to bond when the reconstructed gelatin is older than a month. However, new phantoms can be built quickly and easily using fresh gelatin while recycling other components.
Ultrasound detected liver fat infiltration in 82% of cases measurable by (1)H MRS, while liver fat was detectable in 44% of cases graded absent by ultrasound. Ultrasound grading was subjective, with the radiologists in agreement in 53% of cases (kappa = 0.39, P = 0.002). Considerable overlap in intrahepatocellular lipid content was observed between different grades: absent (0.0-1.58%), mild (2.2-16.2%), moderate (4.9-26.7%) and severe (8.1-76.8%) steatosis. Ultrasound could not detect liver fat levels below 2% as measured by (1)H MRS Conclusion: Ultrasound is less sensitive than (1)H MRS in detecting very low levels of liver fat content, but is sensitive to fatty infiltration greater than 2%. There is a tendency of higher ultrasound grades to correlate with higher degrees of fatty infiltration, although some overlap exists. Our findings are still consistent with ultrasound being useful as a low cost screening tool.
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