We conclude the following: (i) the expression of laminin-5 gamma 2 is a late event in cervical carcinogenesis increasing with the grade of dysplastic lesions; (ii) laminin-5 gamma 2 expression facilitates the identification of invasive and microinvasive lesions which could be difficult to diagnose on the basis of routine stains; (iii) laminin-5 gamma 2 expression in HSILs could potentially identify those lesions with a more increased risk of tumor progression.

There are various possibilities for treating cornual ectopic pregnancies, including medical approaches using methotrexate and surgical approaches using laparoscopy. This report describes the laparoscopic management of a large cornual ectopic pregnancy associated with a high b-human chorionic gonadotropin level and reviews the techniques and outcomes of conservative treatment described in the literature.