SummaryMaternal obesity in pregnancy is associated with a number of adverse outcomes for mother and her offspring both perinatally and later in life. This includes recent evidence that suggests that obesity in pregnancy may be associated with central nervous system problems in the foetus and newborn. Here, we systematically review studies that have explored associations between maternal overweight and obesity in pregnancy and cognitive, behavioural and emotional problems in offspring. The 12 studies eligible for this review examined a wide range of outcomes across the lifespan and eight provided evidence of a link. These data suggest that the offspring of obese pregnancies may be at increased risk of cognitive problems and symptoms of attention deficit hyperactivity disorder in childhood, eating disorders in adolescence and psychotic disorders in adulthood. Given the limitations of existing data, these findings warrant further study, particularly in light of the current worldwide obesity epidemic.

Objective: To study child mental health, parental support, and social support of children with epilepsy as these relate to quality of life (QOL) using child self-report, seizure-related variables, and estimated verbal intelligence based on receptive vocabulary. Methods:A cross-sectional structural equation model of baseline data from the QUALITÉ cohort study, which includes 6 Canadian child epilepsy ambulatory programs. A sample of 3,481 children were screened for the following eligibility: 8 to 14 years of age, with active or medicationmanaged epilepsy. Of 894 eligible children, 506 agreed to participate, of whom 26 were then excluded because of an inability to self-report based on a standard cutoff score of receptive vocabulary lower than 70. The primary outcome of child-reported QOL was measured using the Child Epilepsy QOL Questionnaire.