：Plasmacytosis circumorificialis (PC) , a benign inflammatory mucosal disease rarely found around orifices of the body, is histologically characterized by dense plasma cell infiltration. A 56-year-old woman presented with bandlike redness of the anterior mandibular gingiva with superficial pain. Histopathologically, inflammatory cell infiltration including mainly plasma cells was observed. Immunohistochemical staining revealed these cells were positive for immunoglobulin kappa and lambda light chain. Treatment for periodontal disease and topical steroid application worked well to resolve the symptoms. On the basis of the clinical and histopathological findings, we diagnosed PC of the anterior mandibular gingiva. Key words：plasmocytosis circumorificialis, plasma cell gingivitis, gingiva

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：In todayʼs aging society, the number of patients suffering from taste disorders is increasing. The most frequent cause of taste disorder in older people is drug-induced ; this is a serious side effect that affects the ability of older people to lead healthy lives. Therefore, it is necessary to assess the dissemination of information and establish a system for intervention as soon as possible. Herein we describe four cases of drug-induced taste disorder caused by amlodipine besylate, topiramate, tegafur, and prednisolone. Key words：drug-induced taste disorder, taste abnormality, amlodipine besylate