A B S T R A C TA total number of 80 Wister male rats, 9 -wk. old were taken, weighed and divided into four experimental groups to investigate the effect of Deltamethrin (DLM) oral administration (0.87, 8.7 and 17.4 mg/kg B.W) for a period of 9 weeks on reproductive organs and fertility indices of Wister male rats. The results indicated that DLM caused a significant reduction in Testis weights, sperm count, motility and viability and fructose in semen. Also induced decreases in serum FSH, LH and Estradiol levels however increase in sperm abnormalities. These results indicated that DLM is a toxic pyrethroid pesticide that produced significant reproductive toxicity in treated male rats as revealed by the severely affected parameters (Key word: DLM, Reproductive toxicity, Sperm quality) (http://www.bvmj.bu.edu.eg) (bvmj, 35 (1): 311-318, SEPT.., 2018)

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A B S T R A C TA total number of 80 Wister male rats, 9 -wk. old were taken, weighed and divided into four experimental groups to evaluate the oral toxicity induced by Deltamethrin (DLM) administration (0.87, 8.7 and 17.4 mg/kg B.W) for a period of 9 weeks on Iron homeostasis and inflammatory markers of Wister male rats. The results indicated that DLM was associated with a statistically significant elevated in levels of Interluken2(IL2), Interluken6(IL6), Histamine, cortisol, Ammonia, Haptoglobulin, Transferrin and total iron binding capacity (TIBC), while decreased in Iron (Fe) and Ferritin levels was recorded. These results indicated that DLM is a toxic pyrethroid pesticide that produced significant Alteration in Iron Homeostasis and inflammatory markers. (Key word: DLM, Iron Homeostasis, inflammation) (http://www.bvmj.bu.edu.eg) (bvmj, 35(1): 319-326, SEPT., 2018)