No abstract

Normal colloid uptake by a focal hepatic mass is virtually diagnostic.However, in the patients in whom the colloid scan shows decreased or absent uptake, angiography may show findings diagnostic of focal nodular hyperplasia in up to 75% of cases, thus avoiding the need for liver biopsy or surgery.

A183outcomes. One-way, two-way, and probabilistic sensitivity analyses were used to examine uncertainty in the estimates. Results: Clozapine dominated the three therapies it was compared to and had negative ICERs compared to each of these therapies: -£8,773/QALY, -£20,659/QALY, and -£2,226/QALY, compared to olanzapine, quetiapine, and risperidone respectively. The results from the one-way and two-way sensitivity analyses suggested the findings were insensitive to changes in single model parameters of the top five key drivers and double model parameters of the top two key drivers for all treatment scenarios. The mean ICER values from the probabilistic sensitivity analysis were -£8,737.40/QALY for clozapine versus olanzapine, and -£20,562.56/QALY and -£2,020.44/QALY for quetiapine and risperidone respectively. The probability of clozapine being cost effective compared to olanzapine at a threshold value of £20,000/QALY was 99.98% and 98.44% compared to risperidone. However the probability of clozapine being cost effective compared to quetiapine was 100% at any threshold value. ConClusions: Clozapine was the dominant treatment for treatment-resistant schizophrenia as it was associated with the lowest costs and highest QALYs. Based on these findings the treatment strategy for treatment-resistant schizophrenia ought to be reviewed and clozapine considered after one unsuccessful trial with any other antipsychotic drug.

No abstract

A17 related to both total time and time after Katrina. CONCLUSIONS: Hurricane Katrina was found to be a key factor in the significant decrease in the number of patients that received anti-epileptic medications post-Hurricane Katrina. This may also explain why there were significant decreases in the numbers of ER visits, anti-epileptic medications obtained and the average cost of paid claims for anti-epileptic drugs. In effect, Katrina had both short-and long-term negative effects on epileptic patients' access to care.