We administered bevacizumab intravitreally to treat a recurrence of CNV after confocal laser coagulation and photodynamic therapy in a 32-year-old female patient with a single functional eye. Before and after treatment the vision in the affected eye was stable at 1.0. Before administration of the VEGF antibody leakage was distinctly seen on fluorescein angiography, which did not appear on examination after the treatment. Despite the entailed measure of risk we decided in favour of intravitreal application because it seemed promising in view of earlier positive clinical experience with it in exsudative AMD and macular oedema following central retinal vein occlusion. Intravitreal bevacizumab is an alternative that should also be considered for the treatment of idiopathic CNV. Careful clinical studies will follow.
SummaryDas Lymphsystem durchzieht als „sekundäres Einbahnstraßen-Gefäßsystem“ den Körper und übernimmt zentrale Aufgaben im Bereich Immunsystem, Nährstofftransport und Entsorgung. Zu den wichtigen Differenzialdiagnosen zählen Lymphangitis, (Non-)Hodgkin-Lymphome und Multiple Myelome. Viel häufiger weisen Auffälligkeiten im Lymphbereich – insbesondere Lymphknotenschwellungen und Lymphödeme – jedoch auf Erkrankungen außerhalb des Lymphsystems hin. Generalisierte oder lokale Veränderungen von Lymphknoten hinsichtlich Druckdolenz, Verschieblichkeit, Schwellung und Konsistenz lassen auf verschiedene Pathologien schließen, darunter Infektionen, Malignome und Autoimmunerkrankungen.
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